COENZYME FOR ACETYLATION, A PANTOTHENIC ACID DERIVATIVE
نویسندگان
چکیده
منابع مشابه
The Liberation of Pantothenic Acid from Coenzyme
It was reported previously that coenzyme A contained pantothenic acid bound in such a manner as to make it unavailable in microbiological tests (1). A liberation of p;alanine on acid hydrolysis indicated early the presence of pantothenic acid, which was confirmed by chick assay (2). While the chick assay for pantothenic acid and the p-alanine assay by the yeast growth test yielded equivalent am...
متن کاملThe pantothenic acid content of coenzyme A by chick assay.
Lipmann, Kaplan, Novelli, Tuttle, and Guirard (1) reported that, whereas concentrates of the coenzyme required for acetylation (coenzyme A) showed no pantothenic acid activity by the ordinary microbiological assay, considerable amounts of p-alanine were found after acid hydrolysis. From this early observation, it was suspected that the coenzyme might contain combined pantothenic acid which was ...
متن کاملThe liberation of pantothenic acid from coenzyme A.
It was reported previously that coenzyme A contained pantothenic acid bound in such a manner as to make it unavailable in microbiological tests (1). A liberation of p;alanine on acid hydrolysis indicated early the presence of pantothenic acid, which was confirmed by chick assay (2). While the chick assay for pantothenic acid and the p-alanine assay by the yeast growth test yielded equivalent am...
متن کاملThe effect of pantothenic acid deficiency on acetylation in rats.
The ability of normal and pantothenic acid-deficient rats to acetylate a foreign substance was compared by injection of p-aminobenzoic acid (PAB) and the subsequent measurement of the acetylated PAB excreted. Young male rats weighing around 100 gm. or mature rats averaging over 300 gm. were used in various experiments. Those selected for pantothenate deficiency were given a purified diet free o...
متن کاملThe Effect of Pantothenic Acid Deficiency on Acetylation in Bats*
The ability of normal and pantothenic acid-deficient rats to acetylate a foreign substance was compared by injection of p-aminobenzoic acid (PAB) and the subsequent measurement of the acetylated PAB excreted. Young male rats weighing around 100 gm. or mature rats averaging over 300 gm. were used in various experiments. Those selected for pantothenate deficiency were given a purified diet free o...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1947
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(17)30973-0